Course description

Biopython is a collection of open-source tools and libraries for computational biology and bioinformatics. It provides functionality for working with biological data, including sequence analysis, file parsing, and database querying. Biopython supports multiple bioinformatics formats, such as FASTA, GenBank, and others. It also includes tools for alignment, 3D structure analysis, and phylogenetic tree construction. Biopython is widely used by researchers and developers to streamline data analysis and solve complex problems in biological research.

What will i learn?

  • demonstrate proficiency in parsing and manipulating biological sequences using Biopython, including the ability to perform basic sequence operations, work with different file formats, and connect with biological databases. (L2)
  • master advanced multiple sequence alignment techniques in Biopython, showcasing their ability to create, manipulate, and analyze complex sequence alignments. They will proficiently apply popular alignment tools such as ClustalW and MUSCLE to align diverse biological sequences. (L4)
  • exhibit expertise in designing and executing sophisticated bioinformatics workflows using Biopython. They will demonstrate mastery in tasks such as sequence search (BLAST), database querying (Entrez), and advanced phylogenetic analysis, showcasing proficiency in handling large datasets and utilizing external applications like PAML. (L6)

Text books & references

  • Python: Version 3.6 or higher.
  • Biopython: Installable via pip using the command pip install biopython
  • NumPy: For numerical operations, which is often used alongside Biopython.
  • Other dependencies: Depending on the specific functionalities used (e.g., BioSQL, Matplotlib for visualization, or pandas for data handling).
  • Optional packages: For more advanced bioinformatics tasks, additional packages like scipy, matplotlib, or pillow may be required.

Ganesh Aurora

Free

Modules

19

Skill level

Beginner

Expiry period

Lifetime

Related courses